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In a revised consensus statement for AF surgery was publishe
2019-04-24
In 2012, a revised consensus statement for AF surgery was published by the Heart Rhythm Society/European Heart Rhythm Association/European Cardiac Arrhythmia Society as a part of the “Expert consensus statement for catheter and surgical ablation for AF” [7]. The statement was focused mainly on the r
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nobiletin br Results br Discussion We identified a novel het
2019-04-24
Results Discussion We identified a novel, heterozygous nonsense SCN5A mutation, Q779X, in a family with overlapped phenotype with progressive conduction defects and BrS. The proband suffered from SSS at the age of three, and subsequent ventricular fibrillation with a coved type Brugada ECG pat
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br In their Comment on the use of antenatal
2019-04-24
In their Comment on the use of antenatal corticosteroids to reduce preterm infant deaths, Kishwar Azad and Anthony Costello advise “extreme caution” before scale-up in low-income settings. They emphasise maternal sepsis as a concern but cite only one trial in which dexamethasone resulted in a sig
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br Introducci n Las encendidas palabras
2019-04-24
Introducción Las encendidas palabras de fray Servando Teresa de Mier provienen del Discurso preliminar que acompaña la reedición de la Brevíssima relación de la destruyción de las Indias de fray Bartolomé de las Casas, publicado en México en 1812. Fray Servando no duda en calificar al dominico, l
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irak inhibitor Entretanto quando as elei es
2019-04-24
Entretanto, quando as eleições presidenciais se aproximaram em 1990 o país vivia um momento bastante diferente, marcado não somente pelos agudos problemas econômicos já descritos, mas também pelo incremento da ação militar urbana de Sendero Luminoso, uma vez que irak inhibitor partir de 1989 sua lid
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Una vez que simplifican la problem tica
2019-04-24
Una vez que simplifican la problemática latinoamericana al ámbito de la violencia, dice el autor español, “lo único que parece interesar histamine receptor antagonist los de fuera es si el uso de la violencia está justificado o no”, y la respectiva petición de clarificación a los teólogos de la libe
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Case report A year old Caucasian male who
2019-04-24
Case report A 76 year-old Caucasian male who was evaluated in an emergency department due to headache in May 2001 and was found to have a right parietal subdural hematoma (SDH). Baseline blood work revealed thrombocytopenia of 50×109/L. His SDH was managed with surgical evacuation with full recover
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Pharmacological inhibition of PI K induces apoptosis of CLL
2019-04-24
Pharmacological inhibition of PI3Kα induces apoptosis of CLL dpp-4 inhibitor in vitro [5,18], and inhibits CLL migration towards CXCL12 [5]. The PI3Kα/δ inhibitor copanlisib induces significantly greater apoptosis of CLL cells compared to idelalisib (IC50 of 450nM and >10μM, respectively) in vitro
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br Discussion Metastatic RCC is
2019-04-23
Discussion Metastatic RCC is a fatal disease with survival often measured in months, rather than years. Surgery alone is the standard of care for patients who present with isolated renal disease at the time of diagnosis. However, approximately 1/3 of these patients will go on to develop clinicall
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El segundo estudio lo presenta
2019-04-23
El segundo estudio lo presenta Diana Sofía Sánchez, quien aborda de Rosa Beltrán. Texto en el que nos convida de su propuesta basada en: 1 la representación de la familia relacionada con su búsqueda de normalidad, y 2º la reconstrucción puntual de los fracasos y absurdos de la política mexicana. La
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The region is also suffering from administrative negligence
2019-04-23
The region is also suffering from administrative negligence, extreme poverty, lack of basic health facilities, and weak infrastructure, which have increased its vulnerability to the climatic misery. Travel time to the nearest health facility is 2–4 h, at a cost of PKR 1000–4000 (US$10–40) in a regio
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Los dedos son las cuatro mil verdades vistas
2019-04-23
Los dedos son las cuatro mil verdades vistas por los ojos de las moscas. La labor del escritor, entonces, se pone glucosamine sulfate la altura de la labor del detective: encontrar los diez dedos, descubrir el cuerpo flotando en el agua, dar con una cabeza que yace en el fondo de un río y nombrarla
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Leong et al reported a similar
2019-04-23
Leong et al. reported a similar case of a short circuit in the Riata 1570 defibrillator lead, which manifested as unsuccessful defibrillation [10]. In this case, product analysis of generator indicated structural device damage owing to a short circuit in the defibrillation lead. Marenco et al. also
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br Authorship br Conflict of interest
2019-04-22
Authorship Conflict of interest disclosure Introduction The Aurora kinases are serine/threonine protein kinases essential for regulation of normal ARQ197 mitosis. Aurora kinases A (AAK) and B are overexpressed in hematologic malignancies, including acute myeloid leukemia (AML) and myelodys
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igf1r The NKG D NKG DL system has an
2019-04-22
The NKG2D/NKG2DL system has an important role in tumor immune surveillance, and the NKG2D-activating receptor is expressed in various immune cells, including NK cells, NK T cells, and CD8+ T cells. MICA is one of the NKG2D ligands and is rarely expressed on healthy cells; however, its expression may
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