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That well established data for Sapindaceae
2019-04-19
That well-established data for Sapindaceae toxicity have long existed from clinical experience in Africa and the Caribbean is an important lesson for global health and neurotoxicology. A worldwide understanding of the adverse effects on the nervous system of both naturally occurring as well as synth
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The primary tool in the pharmacological management
2019-04-19
The primary tool in the pharmacological management of PTSD is the use of selective serotonin reuptake inhibitors [55,56], but positive response rates are generally limited. In addition, non-pharmacological treatment such as CBT has been shown to be effective for PTSD [57]. Psychological distress
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Las formas literarias de presentaci n de
2019-04-19
Las formas literarias de presentación de los textos aquí comentados son distintas: estamos frente a una obra de teatro, dos artículos (o capítulos de libro) y un cuento. El establecimiento de una ‘periodización’ de la historia de la literatura mexicana a partir de cuatro etapas —la prehispánica,
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br Methods br Results Characteristics
2019-04-19
Methods Results Characteristics of studies included in the analysis are described in the accompanying Lancet paper. We included 119 studies (58 from high-income countries and 61 from low-income and middle-income countries) in this csf-1r analysis. Worldwide in 2010, an estimated 11 569 538 e
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Tuberculosis case finding and diagnostics are far
2019-04-19
Tuberculosis case-finding and diagnostics are far from perfect. The worldwide case detection rate of tuberculosis has stagnated at around 60%, not reaching the target of 70% originally set for 2000 but postponed to 2005, and then judged to be unreachable. In sub-Saharan Africa, case detection rates
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South Africa was the first African country to implement the
2019-04-18
South Africa was the first African country to implement the seven-valent pneumococcal conjugate vaccine (PCV7) in its routine infant immunisation programme (in 2009), with the novel schedule aligned to WHO\'s recommended Expanded Programme on Immunisation (EPI)—ie, a 2 + 1 schedule with doses at age
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Human p MAPK is stimulated by various inflammatory cytokines
2019-04-18
Human p38 MAPK is stimulated by various inflammatory cytokines and cellular stresses [46]. Especially, the p38 MAPK signaling pathway is a crucial modulator of proinflammatory cytokine biosynthesis at the transcriptional and translational levels [46]. Furthermore, studies revealed that p38 MAPK regu
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peptide yy In the current era nearly all cases of hormone re
2019-04-18
In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud
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The answer is D This patient had
2019-04-18
The answer is D. This patient had a typical Brugada type 1 ECG pattern. Coved ST-segment elevation of more than or equal to 2mm in at least either lead V1 or V2 with T-wave SC 144 is considered typical type 1 pattern; this was not STEMI, and hence, option 1 is incorrect. As per the 2015 European So
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Any abnormality causing a loss
2019-04-18
Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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Introduction Neuroblastoma NB which arises from embryonal ne
2019-04-18
Introduction Neuroblastoma (NB), which arises from embryonal neural crest cells, is the most common extra-cranial solid tumor of childhood and accounts for more than 15% of all child cancer death [1,2]. Patients with NB frequently manifest disseminated disease at first visit and prognosis of these
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br Short case report A year
2019-04-18
Short case report A 65-year-old man with persistent AF underwent multi-detector computed tomography (CT) before catheter ablation. An anomalous muscular band connecting the posterior side of the left atrial roof and the right edge of fossa ovalis in the left atrium was detected (Fig. 1). During
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Preamble The J wave syndromes JWSs consisting of the
2019-04-18
Preamble The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS), have captured the interest of the cardiology DMH-1 over the past 2 decades following the identification of BrS as a new clinical entity by Pedro and Josep Brugada in 1992 [1]. Th
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br Diarrhoeal diseases are the second most common
2019-04-18
Diarrhoeal diseases are the second most common cause of deaths of children, killing more than 1·5 million children annually and infecting billions more. The recently released Global Action Plan for Pneumonia and Diarrhoea (GAPPD) is a comprehensive strategy document outlining plans to end preventa
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hcv protease inhibitors Situaci n que aparece como un tema d
2019-04-18
Situación que aparece como un tema de reflexión filosófica, tanto por los discursos que produce tal situación descrita como por las cuestiones éticas que suscita, por ejemplo: el problema ético de la justicia en tanto que los pueblos originarios no han sido objeto de ella desde las políticas moderna
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