• br Discussion A familial platelet disorder with a propensity

  2019-06-18

  

  Discussion A familial platelet disorder with a propensity to myeloid malignancy (FPD/MM) was first reported in 1978 and since then approximately 30 pedigrees with RUNX1 germline mutations have been reported in the literature [9,11]. The RUNX1 gene is composed of 10 exons (1–6, 7A, 7B, 7C and 8).

• br Discussion Bone marrow fibrosis is

  2019-06-18

  

  Discussion Bone marrow fibrosis is known to be associated with hematolymphoid malignancies such as acute leukemia, Hodgkin and non-Hodgkin lymphoma. Among the acute leukemias, marrow fibrosis is most often seen with acute megakaryoblastic leukemia. It is an uncommon finding in APL and till date o

• AZD 5153 br Conclusion br Source of funding br Acknowledgeme

  2019-06-18

  

  Conclusion Source of funding Acknowledgement Arsenic is widely dispersed throughout nature, and its toxic effect in humans, which focus mainly on somatic cells, as well known. Epidemiological research and in vitro testing have shown that long-term contact with arsenic can induce the forma

• The recently published global consensus recommendations

  2019-06-18

  

  The recently published global consensus recommendations on prevention and management of rickets advocate for the eradication of rickets and osteomalacia through implementation of national supplementation and food fortification programmes containing vitamin D, calcium, or both. On the basis of high-q

• br In the past year migration to

  2019-06-18

  

  In the past year, migration to Europe from Africa and the Middle East has reached unprecedented levels. In 2016, 181 405 migrants reached the shores of Italy and more than 5000 died trying to reach the southern coasts of Europe. Many migrants seek to escape war, poverty, persecution, or ill treatm

• The presence of AHRE however may not invariably indicate the

  2019-06-18

  

  The presence of AHRE, however, may not invariably indicate the presence of ATA. We have recently reported AHRE that reflected episodes of atrial fibrillation (AF) as well as device-mediated arrhythmic events, such as repetitive non-reentrant ventriculo-atrial synchrony (RNRVAS), PPM-18 mediated tac

• br Conclusion br Conflict of interest br Introduction br

  2019-06-18

  

  Conclusion Conflict of interest Introduction Future challenges and conclusion In recent decades several anticancer drugs have been approved for the management and treatment of colorectal cancer. These drugs do not represent a revolution in the treatment of CRC. However, 5-FU has continue

• br Postoperative rehabilitation Although surgery is the main

  2019-06-18

  

  Postoperative rehabilitation Although surgery is the main curative therapy for lung cancer, the procedure can directly cause a reduction in pulmonary functional reserve and exercise capacity proportional to the extent of resection. The problems might be more severe in those undergoing multimodali

• New ACLS guidelines emphasize the importance of external che

  2019-06-17

  

  New ACLS guidelines emphasize the importance of external chest compressions (ECCs), stressing that ECCs should be performed to the correct depth and frequency to guarantee effectiveness [61]. Without gravity, the crewmembers cannot do ECCs in the same way as in a hospital because of Newton\'s third

• Chronic myelomonocytic leukemia has been reported as the mos

  2019-06-17

  

  Chronic myelomonocytic leukemia has been reported as the most prevalent concomitant hematological neoplasm, followed by myelodysplastic, myeloproliferative syndrome, and acute myeloid leukemia; on the other hand, Lymphoproliferative neoplasms were less frequency associated with SM-AHMND. In another

• In a recent study Nademanee et al reported additional

  2019-06-17

  

  In a recent study, Nademanee et al. [76]. reported additional evidence pointing to pathologic changes in the RVOT of patients with BrS that have proved undetectable by echocardiography or MRI. In contrast, imaging techniques in ARVC clearly display morphologic and functional changes (e.g., dilation

• In the context of our present work that uses

  2019-06-17

  

  In the context of our present work that uses total community treatment with azithromycin for yaws eradication, we would support an empirical approach to treatment. Azithromycin is effective for treatment of both and , so our mass treatment should be effective for both causes of skin ulcer. isolate

• Universalisation means reaching all individuals

  2019-06-17

  

  Universalisation means reaching all individuals with good quality, effective interventions without financial hardship. Coverage matters. Participatory women\'s groups are effective in reducing newborn mortality among poor populations provided they involve about 30% of pregnant women in the populatio

• El neocl sico arquitect nico que se empez a utilizar

  2019-06-17

  

  El neoclásico arquitectónico que se empezó (+)-Usniacin utilizar fue trasunto del neoclásico bonapartista, más que del griego: lo vio María Rosa Lida en los remozamientos de la catedral de Buenos Aires por obra de Bernardino Rivadavia, recuerdo francés más que griego y deseo de cortar con la tradici

• br Sebastian Vollmer and colleagues April

  2019-06-17

  

  Sebastian Vollmer and colleagues (April, 2014) conclude that “the contribution of economic growth to the CK 666 in early childhood undernutrition in developing countries is very small, if it exists at all”. Progress will therefore require a shift from “the so-called trickle-down approach of a gro

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