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Gene regulation of MMPs is
2023-12-28

Gene regulation of MMPs is influenced by the transcription factor activating factor-1 (AP-1). AP-1 complexes are heterodimers of proteins of the two proto-oncogene families (jun and fos) and have tie2 in the promoter region of MMPs, as well as in genes mediating inflammatory responses. The transcri
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salinomycin According to the phytochemical screening Lophira
2023-12-28

According to the phytochemical screening, Lophira procera is rich in phenolic compounds including total polyphenols, total flavonoids, tannins and proantocianidins. It has been reported that there is a correlation between total polyphenol content and antioxidant activity [29]. The present invention
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Y-27632 br AR mediated actions in cells of the vascular
2023-12-28

AR-mediated actions in Y-27632 of the vascular wall Sex hormones may influence the size and composition of atherosclerotic lesions indirectly by modifying systemic cardiovascular risk factors such as plasma lipids profiles and insulin sensitivity; this aspect of their action is discussed elsewhe
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Constitutive tyrosine kinase activity of BCR
2023-12-28

Constitutive tyrosine kinase activity of BCR/ABL fusion genes causes uncontrolled cell growth and is also thought to be responsible for a variety of changes in normal cellular functions like differentiation, adhesion, migration and apoptotic response in CML. Therefore it is important to know the exp
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Fig A shows a schematic representation of histological resul
2023-12-28

Fig. 2A shows a schematic representation of histological results according to the Franklin and Paxinos Mouse Brain Atlas (2001). The black circles represent the sites of drug infusion that were on-target within the amygdala. Gray circles represent the animals that had infusion locations outside the
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When added to the culture medium extracellular ATP is
2023-12-28

When added to the culture medium, extracellular ATP is metabolized into adenosine by ectonucleotidases, and ARs are then activated by adenosine with concentrations in the micromolar range [27]. However, our study showed that activation of ARs by exogenous adenosine could not induce the odontoblastic
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br Acknowledgements Authors wish to thank Sabanci University
2023-12-27

Acknowledgements Authors wish to thank Sabanci University (Turkey), Tubitak (Cost Eu-Ros, 113Z463), and the University of Turin (Italy) for supporting this work. Beyza Vurusaner is supported by Sabanci University Post-doctoral research scholarship. Introduction Endometriosis is defined as the
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Comparison of the GLUT positive plus ACLY negative group wit
2023-12-27

Comparison of the GLUT1-positive plus ACLY negative group with the GLUT1-negative plus ACLY positive group indicated no significant difference with respect to disease-free survival and overall survival. However, some obvious differences in histological types were found in their formation. A previous
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Cerebral ischemia occurs following the occlusion of a cerebr
2023-12-27

Cerebral ischemia occurs following the occlusion of a cerebral artery by a thrombus and causes cell swelling due to cytotoxic edema and BBB disruption with vasogenic edema (Loreto and Reggio, 2010, Nakaji et al., 2006, Shibata et al., 2004). Vasogenic edema is directly linked to alteration of the BB
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In the current study SA
2023-12-27

In the current study, SA was assessed to confirm the safety of CS addition to erythrocytes SA as well as SA elicits antioxidant action. It has been reported that, ROS induced desialylation by depletion of SA content from cell surfaces (Pawluczyk et al., 2014, Harisa, 2015). Therefore, significant d
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The MOB and AOB are important in ungulates Keller and
2023-12-27

The MOB and AOB are important in ungulates (Keller and Levy, 2012, Sanchez-Andrade and Kendrick, 2009), which rely heavily on odorant information for social interactions (Baum and Cherry, 2015, Keller and Levy, 2012, Osada et al., 2014, Villagran and Ungerfeld, 2013). The release of GABA and glutama
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The current findings proved that citral treatment induced
2023-12-27

The current findings proved that citral treatment induced mitochondrial-mediated apoptotic cell death in both HCT116 and HT29 through the p53 and ROS. As such, citral promoted apoptosis as evident by the externalization of PS and dissipation of Δψm at 24h of treatment in HCT116 and HT29 cells. These
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There are several AP binding sites in the sequence of
2023-12-27

There are several AP-1 Cefepime Dihydrochloride Monohydrate in the sequence of TIMP-1 promoter [18,19]. EBV could up-regulate TIMP-1 expression by binding to the AP-1 site in the TIMP-1 promoter [18]. IL-32, a newly multi-function cytokine, could activate AP-1, NF-κβ, p38MAPK signal pathways, and i
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br Materials and methods br Results br Discussion Pulmonary
2023-12-27

Materials and methods Results Discussion Pulmonary fibrosis is a progressive and chronic lung disease and its typical features include Tariquidar methanesulfonate, hydrate proliferation, epithelial injury, chronic interstitial inflammation, increased extracellular matrix (ECM) production,
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Overall we found maternal antibiotics to be associated with
2023-12-27

Overall, we found maternal cholesterol absorption inhibitors to be associated with improved outcomes. In these multiple logistic regression models, high postnatal empiric infant antibiotic exposure was not significantly associated with risk for NEC or LOS. However, consistent with previous studies,
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